A Japanese research team said Wednesday it has reproduced the pathological condition of muscular dystrophy by using induced pluripotent stem, or iPS, cells.
The team, which includes Hidetoshi Sakurai of Kyoto Universitys Center for iPS Cell Research and Application, reproduced ailing skeletal muscle cells seen in sufferers of Miyoshi myopathy, a type of muscular dystrophy, from iPS cells, the team said.
It is the first such achievement in the world and was reported in an article in U.S. journal PLOS One.
One of the symptoms of Miyoshi myopathy is destruction of cell membranes of the skeletal muscle cells. But the team succeeded in restoring membrane repair functions by activating special proteins usually lacking in those with the disease.
Read the rest of the story: Japan Team Reproduces Muscular Dystrophy Condition with iPS Cells